Best Suppliers of HPLC Worldwide

High-Performance Liquid Chromatography (HPLC) has become an essential technique in analytical chemistry, used extensively for separating, identifying, and quantifying components in a sample. As demand for HPLC systems and accessories grows, numerous global suppliers offer advanced HPLC instruments, reagents, columns, and consumables. Each supplier provides unique features, technologies, and support, allowing them to cater to diverse industries such as pharmaceuticals, environmental testing, biotechnology, and food safety.

In this guide, we’ll explore the top global suppliers of HPLC systems, highlighting their key features and contributions to the field.


1. Agilent Technologies

Headquarters: Santa Clara, California, USA
Website: www.agilent.com

Key Features:

  • Wide Range of HPLC Systems: Agilent is known for offering a broad selection of HPLC systems, from conventional HPLC to Ultra-High-Performance Liquid Chromatography (UHPLC).
  • InfinityLab LC Series: Their flagship product line, which includes systems like the 1260 Infinity II and 1290 Infinity II, provides flexibility in choosing between high-resolution separations and ultra-fast analysis.
  • Method Development Tools: Agilent offers advanced software for method development, including OpenLAB CDS and ChemStation, making data acquisition, analysis, and reporting streamlined.
  • Comprehensive Consumables: Agilent offers HPLC columns, fittings, vials, and solvents, including ZORBAX columns, known for their robustness and reproducibility.
  • Global Support and Training: With a strong global presence, Agilent provides 24/7 customer support, extensive online resources, and training programs, ensuring that customers get maximum performance from their systems.

Industries Served:

  • Pharmaceuticals
  • Environmental Analysis
  • Clinical Diagnostics
  • Food Safety

2. Thermo Fisher Scientific

Headquarters: Waltham, Massachusetts, USA
Website: www.thermofisher.com

Key Features:

  • Dionex HPLC Systems: Thermo Fisher offers a wide range of chromatography solutions, including the Dionex line for liquid chromatography and ion chromatography. The Vanquish UHPLC system is one of their standout offerings.
  • Advanced Detectors: Thermo Fisher provides a wide array of detectors, including mass spectrometry (MS) detectors that offer high sensitivity for trace analysis.
  • Chromeleon Chromatography Data System (CDS): A popular choice for data management and instrument control, Chromeleon CDS integrates seamlessly with HPLC systems to offer comprehensive workflows and report generation.
  • Sustainability Focus: Many of Thermo Fisher’s consumables, such as chromatography solvents and columns, are designed with an emphasis on sustainability and environmental friendliness.
  • Ion Chromatography Expertise: Thermo Fisher is a leader in ion chromatography, making it ideal for applications requiring trace analysis of ions and small molecules, particularly in environmental and water testing.

Industries Served:

  • Pharmaceuticals
  • Biotechnology
  • Environmental Testing
  • Chemical Research
  • Clinical Laboratories

3. Waters Corporation

Headquarters: Milford, Massachusetts, USA
Website: www.waters.com

Key Features:

  • ACQUITY UPLC Systems: Waters Corporation is renowned for its Ultra-Performance Liquid Chromatography (UPLC) systems, which provide faster and more sensitive separations. Their ACQUITY UPLC series is a game-changer in industries requiring high-resolution separations and fast runtimes.
  • Empower 3 CDS: Waters’ Empower software simplifies data management and method development, allowing scientists to analyze data more efficiently.
  • Mass Spectrometry Integration: Waters excels in combining HPLC with advanced mass spectrometry systems like the Xevo G2-XS QTof, providing powerful analytical capabilities for complex mixtures.
  • Wide Range of Columns: Waters offers a comprehensive range of HPLC columns, including the BEH and HSS columns, which are known for their stability under extreme conditions.
  • Alliance HPLC: A trusted workhorse for laboratories, the Waters Alliance HPLC system provides reliability, reproducibility, and high throughput for routine analysis.

Industries Served:

  • Pharmaceuticals
  • Food and Beverage
  • Environmental Science
  • Life Sciences

4. Shimadzu Corporation

Headquarters: Kyoto, Japan
Website: www.shimadzu.com

Key Features:

  • Nexera UHPLC and Prominence HPLC Systems: Shimadzu is a leader in offering high-performance liquid chromatography systems designed for both routine and high-end analytical needs. Their Nexera UHPLC systems provide ultra-fast separations with high precision and reproducibility.
  • Low Carryover and High Sensitivity: Shimadzu’s systems are designed to minimize carryover between samples, making them ideal for pharmaceutical and environmental applications where contamination is a concern.
  • i-Series Integrated HPLC: The i-Series is a user-friendly, compact HPLC system designed for ease of use and high efficiency in routine testing environments.
  • LabSolutions Software: Shimadzu’s LabSolutions platform offers comprehensive software for system control, data analysis, and compliance, ensuring seamless integration into laboratory workflows.
  • Environmentally Conscious Systems: Shimadzu is known for its commitment to sustainability, offering systems designed to minimize solvent consumption and reduce overall environmental impact.

Industries Served:

  • Pharmaceuticals
  • Environmental Testing
  • Biotechnology
  • Clinical Diagnostics
  • Food and Beverage

Global Suppliers of HPLC Systems: Key Players and Their Features

High-Performance Liquid Chromatography (HPLC) has become an essential technique in analytical chemistry, used extensively for separating, identifying, and quantifying components in a sample. As demand for HPLC systems and accessories grows, numerous global suppliers offer advanced HPLC instruments, reagents, columns, and consumables. Each supplier provides unique features, technologies, and support, allowing them to cater to diverse industries such as pharmaceuticals, environmental testing, biotechnology, and food safety.

In this guide, we’ll explore the top global suppliers of HPLC systems, highlighting their key features and contributions to the field.


1. Agilent Technologies

Headquarters: Santa Clara, California, USA
Website: www.agilent.com

Key Features:

  • Wide Range of HPLC Systems: Agilent is known for offering a broad selection of HPLC systems, from conventional HPLC to Ultra-High-Performance Liquid Chromatography (UHPLC).
  • InfinityLab LC Series: Their flagship product line, which includes systems like the 1260 Infinity II and 1290 Infinity II, provides flexibility in choosing between high-resolution separations and ultra-fast analysis.
  • Method Development Tools: Agilent offers advanced software for method development, including OpenLAB CDS and ChemStation, making data acquisition, analysis, and reporting streamlined.
  • Comprehensive Consumables: Agilent offers HPLC columns, fittings, vials, and solvents, including ZORBAX columns, known for their robustness and reproducibility.
  • Global Support and Training: With a strong global presence, Agilent provides 24/7 customer support, extensive online resources, and training programs, ensuring that customers get maximum performance from their systems.

Industries Served:

  • Pharmaceuticals
  • Environmental Analysis
  • Clinical Diagnostics
  • Food Safety

2. Thermo Fisher Scientific

Headquarters: Waltham, Massachusetts, USA
Website: www.thermofisher.com

Key Features:

  • Dionex HPLC Systems: Thermo Fisher offers a wide range of chromatography solutions, including the Dionex line for liquid chromatography and ion chromatography. The Vanquish UHPLC system is one of their standout offerings.
  • Advanced Detectors: Thermo Fisher provides a wide array of detectors, including mass spectrometry (MS) detectors that offer high sensitivity for trace analysis.
  • Chromeleon Chromatography Data System (CDS): A popular choice for data management and instrument control, Chromeleon CDS integrates seamlessly with HPLC systems to offer comprehensive workflows and report generation.
  • Sustainability Focus: Many of Thermo Fisher’s consumables, such as chromatography solvents and columns, are designed with an emphasis on sustainability and environmental friendliness.
  • Ion Chromatography Expertise: Thermo Fisher is a leader in ion chromatography, making it ideal for applications requiring trace analysis of ions and small molecules, particularly in environmental and water testing.

Industries Served:

  • Pharmaceuticals
  • Biotechnology
  • Environmental Testing
  • Chemical Research
  • Clinical Laboratories

3. Waters Corporation

Headquarters: Milford, Massachusetts, USA
Website: www.waters.com

Key Features:

  • ACQUITY UPLC Systems: Waters Corporation is renowned for its Ultra-Performance Liquid Chromatography (UPLC) systems, which provide faster and more sensitive separations. Their ACQUITY UPLC series is a game-changer in industries requiring high-resolution separations and fast runtimes.
  • Empower 3 CDS: Waters’ Empower software simplifies data management and method development, allowing scientists to analyze data more efficiently.
  • Mass Spectrometry Integration: Waters excels in combining HPLC with advanced mass spectrometry systems like the Xevo G2-XS QTof, providing powerful analytical capabilities for complex mixtures.
  • Wide Range of Columns: Waters offers a comprehensive range of HPLC columns, including the BEH and HSS columns, which are known for their stability under extreme conditions.
  • Alliance HPLC: A trusted workhorse for laboratories, the Waters Alliance HPLC system provides reliability, reproducibility, and high throughput for routine analysis.

Industries Served:

  • Pharmaceuticals
  • Food and Beverage
  • Environmental Science
  • Life Sciences

4. Shimadzu Corporation

Headquarters: Kyoto, Japan
Website: www.shimadzu.com

Key Features:

  • Nexera UHPLC and Prominence HPLC Systems: Shimadzu is a leader in offering high-performance liquid chromatography systems designed for both routine and high-end analytical needs. Their Nexera UHPLC systems provide ultra-fast separations with high precision and reproducibility.
  • Low Carryover and High Sensitivity: Shimadzu’s systems are designed to minimize carryover between samples, making them ideal for pharmaceutical and environmental applications where contamination is a concern.
  • i-Series Integrated HPLC: The i-Series is a user-friendly, compact HPLC system designed for ease of use and high efficiency in routine testing environments.
  • LabSolutions Software: Shimadzu’s LabSolutions platform offers comprehensive software for system control, data analysis, and compliance, ensuring seamless integration into laboratory workflows.
  • Environmentally Conscious Systems: Shimadzu is known for its commitment to sustainability, offering systems designed to minimize solvent consumption and reduce overall environmental impact.

Industries Served:

  • Pharmaceuticals
  • Environmental Testing
  • Biotechnology
  • Clinical Diagnostics
  • Food and Beverage

5. PerkinElmer

Headquarters: Waltham, Massachusetts, USA
Website: www.perkinelmer.com

Key Features:

  • Flexar HPLC and UHPLC Systems: PerkinElmer offers the Flexar series of HPLC and UHPLC systems, which provide flexibility in method development and high sensitivity for trace analysis.
  • Comprehensive Detection Solutions: PerkinElmer is known for its variety of detection systems, including PDA (Photodiode Array) and fluorescence detectors that enhance the sensitivity and selectivity of chromatographic analyses.
  • LAMBDA Spectrophotometers: In addition to HPLC systems, PerkinElmer offers UV-Vis spectrophotometers that can be paired with HPLC for comprehensive analytical solutions.
  • OneSource Laboratory Services: PerkinElmer provides end-to-end laboratory services, including instrument maintenance, repair, and compliance services, making it an ideal partner for laboratories looking for integrated solutions.
  • Software Integration: PerkinElmer’s SimplicityChrom software is designed to optimize laboratory workflows by integrating instrument control, data acquisition, and reporting into a single platform.

Industries Served:

  • Pharmaceutical
  • Environmental
  • Food Safety
  • Chemical Industry
  • Clinical Research

6. Hitachi High-Tech

Headquarters: Tokyo, Japan
Website: www.hitachi-hightech.com

Key Features:

  • LaChromUltra HPLC: Hitachi offers advanced HPLC systems such as the LaChromUltra, designed for ultra-fast separations and high sensitivity in routine and complex analyses.
  • Comprehensive Detection Capabilities: Hitachi provides a range of detectors, including UV, PDA, and refractive index detectors, allowing users to select the best detector for their application.
  • Compact and User-Friendly Designs: Hitachi’s HPLC systems are known for their compact designs, making them suitable for laboratories with limited space.
  • Eco-Friendly Solutions: Hitachi is committed to offering energy-efficient HPLC systems, with designs that reduce solvent consumption and operational costs.
  • Easy Maintenance: The modular design of Hitachi’s systems ensures easy maintenance and reduced downtime, making them a reliable choice for long-term use.

Industries Served:

  • Pharmaceuticals
  • Biotechnology
  • Food and Beverage
  • Chemical Industry

7. Bio-Rad Laboratories

Headquarters: Hercules, California, USA
Website: www.bio-rad.com

Key Features:

  • Nuvia HPLC Columns: Bio-Rad is recognized for its Nuvia chromatography columns, which are designed for high-resolution protein purification and biomolecule separations.
  • ChromLab Software: Bio-Rad’s ChromLab software offers seamless control of HPLC systems, simplifying workflows for protein and nucleic acid analysis.
  • Diverse Chromatography Portfolio: In addition to HPLC, Bio-Rad offers a range of chromatography techniques, including size exclusion and affinity chromatography, particularly suited for the biotechnology and life sciences sectors.
  • Bioprocessing Expertise: Bio-Rad is particularly strong in the biopharmaceutical space, providing systems and consumables that cater to large-scale protein purification and biomolecule analysis.

Industries Served:

  • Biotechnology
  • Biopharmaceuticals
  • Academic Research
  • Food and Beverage

Conclusion

The global suppliers of HPLC systems are constantly innovating to meet the demands of industries that require high sensitivity, precision, and reproducibility. Each supplier offers unique strengths, whether it’s the high-speed separations of Waters UPLC systems, the comprehensive software solutions from Agilent, or the eco-friendly and sustainable designs from Shimadzu.

When choosing an HPLC system, it’s important to consider the specific needs of your application, the available support and training, and the long-term reliability of the system. From pharmaceuticals to food safety, these suppliers provide cutting-edge solutions that ensure accurate results and streamlined workflows, making them leaders

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