MCQ Granulations Sections
#1. What is the primary purpose of the Granulations section in an Oral Solids Doses Formulation Plant?
#2. Which process is carried out in the Granulations section to improve flowability and compressibility of the powders?
#3. Granulation is a technique used to:
#4. What is the purpose of adding a binder during the granulation process?
#5. Which of the following granulation methods requires the use of a liquid binder?
#6. Which type of equipment is commonly used for wet granulation in the Oral Solids Doses Formulation Plant?
#7. The primary purpose of the drying step in the granulation process is to:
#8. Which granulation method is preferred when working with heat-sensitive active pharmaceutical ingredients (APIs)?
#9. The size of the granules formed during the granulation process can directly impact:
#10. In the granulations section, the milling process is performed to:
#11. Which of the following statements about excipients used in granulation is true?
#12. The main purpose of quality control checks in the granulations section is to:
#13. Which of the following is NOT a common problem associated with wet granulation?
#14. Which granulation method is considered to be the most cost-effective and straightforward?
#15. The purpose of the milling process after drying the granules is to:
#16. Which parameter is critical to monitor during the granulation process to ensure consistent granule properties and prevent over-wetting of the granules?
#17. What is the typical range of the granule size distribution used for roller compaction?
#18. What is the purpose of adding a glidant during the granulation process?
#19. The Granulation section is responsible for producing granules with a specific bulk density. What is the formula to calculate bulk density?
#20. Which of the following excipients is commonly used as a binder in wet granulation?
#21. During wet granulation, what is the typical range of temperature used in the drying step to remove moisture from the granules?
#22. Which granulation process involves the use of a vacuum to enhance the distribution of the binder solution and improve granule uniformity?
#23. In dry granulation using roller compaction, what is the typical roll force range used to compact the powders into flakes?
#24. What is the acceptable range of granule size distribution for direct compression tableting to ensure uniformity and content uniformity of the final tablets?
#25. In a high-shear granulator, what is the recommended range of impeller tip speed for efficient granulation?
#26. During the granulation process, what is the ideal range for the moisture content of the granules to ensure proper flowability and compressibility?
